
"FRONTIERS
IN BIOLOGY"
by Jonathon M. Sullivan, MD, PhD
FUNDAMENTALS I:
BUILDING BLOCKSATOMS AND BASIC CHEMISTRY FOR LIFE SCIENCES
Program SynopsisIn this issue, your old Quantum Butchers going to start something newa series on frontiers in biology. Well talk about the latest revelations in cell structure and physiology, recombinant DNA and genetic engineering, cell suicide, whats new in neurobiology, cell signaling and other groovy stuff. I wont throw it all at you sequentiallyalong the way Ill be sticking in a few articles on physics, computer science, astronomy and any other topics that jump up in my face. But for the next year or so were going to take a journey through the frontiers of living matteror as I like to call it, the Quantum Meat.
Some of you, Im sure, could dig into the Quantum Meat and feel right at home munchin down on phospholipid bilayers, synaptic vesicles, mitochondrial membranes and retrotransposons. Lets face it: people like you arent normal. Most decent, regular folk last saw a biology text in high school or college, which means, of course, that theyve never had a proper introduction to the life sciences. So were going to start with fundamentals. The first three articles in this series will cover the basics, cooking up the Quantum Meat from scratch, as it were. Were going to start with atoms and work our way up to cells. But even in these introductory articles were going to cover some material you bionerds may find interesting, so dont run off to play with your PCR just yet.
Lets wipe down the older particle cleaver and dissecting tray and get started, shall we?
atomic number and isotopes
ions
atomic weight
periodic table
atomic structure, periodicity, and chemical properties
Lewis structure and the octet rule
the covalent bond
chemical bonds and energy
the ionic bond
metals, nonmetals and chemical bonds
"quantum fuzz," Schrodinger, and the modern atom
the hydrogen bondPolar Molecules--What's So Great About Water?
water as a polar solvent
water as a thallasogen
water and biochemistry
acid-base chemistry--the "ionization" of watermaking a base
acids, bases and pH
making an acidOrganic Chemistry Ain't Biochemistry--But it Helps
Carbon -carbon bonds and organic compounds
modeling organics
representative organic compounds
an organic bestiary
abundance
Bibliography
biogeochemical cycling
carbon bond energy