Work went pretty quickly after that, and by 1965 the genetic code was in hand. It is reproduced for your fun and amazement in Table 1. The table is easy to read. If you want to find out which three nucleotides code for, say, phenylalanine, you locate pheylalanine on the table (upper left corner). Read the first nucleotide from the left colum, the second from the top row, and the third from the right column. You should come up with UUU (Nirenberg and Matthaei did). Molecular biologists say that UUU is a codon for phenlyalanine.
second letter
FIRST LETTER
U
C
A
G
THIRD LETTER
U
Phenylalanine
Phenylalanine
Leucine
LeucineSerine
Serine
Serine
SerineTyrosine
Tyrosine
Stop
StopCysteine
Cysteine
Stop
TryptophanU
C
A
GC
Leucine
Leucine
Leucine
LeucineProline
Proline
Proline
ProlineHistidine
Histidine
Glutamine
GlutamineArginine
Arginine
Arginine
ArginineU
C
A
GA
Isoleucine
Isoleucine
Isoleucine
MethionineThreonine
Threonine
Threonine
ThreonineAsparagine
Asparagine
Lysine
LysineSerine
Serine
Arginine
ArginineU
C
A
GG
Valine
Valine
Valine
ValineAlanine
Alanine
Alanine
AlanineAspartic
Aspartic
Glutamate
GlutamateGlycine
Glycine
Glycine
GlycineU
C
A
GTable 1. The Genetic Code. It's easy to read if you follow the directions in the text.